Blood Pressure Medications Compared: Which Tablets Work Best?
Comprehensive Study
Researchers have now investigated this question. In a secondary analysis of a study with a very large number of participants, they were able to compare the long-term effects of preparations from the most important classes of active ingredients against high blood pressure, diuretics, calcium channel blockers, and ACE inhibitors. Notably, the large number of 32,804 study participants and the long observation period, as they could be followed up for up to 23 years. All participants had mild to moderate high blood pressure at the beginning, as well as at least one other risk factor for cardiovascular diseases. The age of the participants was at least 55 years at the start of the study.
It was investigated whether there are differences in the use of the various medications regarding mortality from cardiovascular diseases or the occurrence of diseases such as heart or kidney diseases or strokes. Was one active ingredient better at preventing this than another?
It was found that none of the three classes of active ingredients is superior to the others. The risk of dying from a cardiovascular disease was nearly the same in all three groups. Also, mortality after strokes was equal in all three groups after several analyses.
The researchers thus confirm that all classes of active ingredients have equally good effects against high blood pressure.
Conclusion:
There is no high blood pressure medication that can universally be considered the best or most effective for every hypertensive patient. Medications from all classes of active ingredients can lower blood pressure comparably well. Thus, an individually suitable medication can be selected for each patient.
Sources:
- https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812523
- https://www.rnd.de/wissen/blutdruckmedikamente-im-langzeit-check-gibt-es-unterschiede-VHZIEH3J2NBEBMPOHNEK5MRF4I.html
- https://lomazoma.com/drei-verschiedene-substanzklassen-wie-gut-welches-blutdrucksenkende-mittel-wirkt/
- https://jamanetwork.com/journals/jama/fullarticle/2803518
By Sabine Croci.
This article is medically reviewed. Last updated (03/2024).
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